Dr. Madhav Thambisetty, MBRF Trustee and Vice Chair, Leading New Project to Diversify Clinical Trial Participation

Valerie PatmintraBrain Health, Cognitive Aging, News

Dr. Madhav Thambisetty, MD, PhD, Trustee and Vice Chair of the McKnight Brain Research Foundation is leading a new research initiative to diversify participants recruited into Alzheimer’s and related dementia clinical trials. Leveraging a telemedicine platform (Ro) that serves a large and decentralized population, the initiative aims to advance new, patient-centric clinical research strategies by creating a Registry for Equal Access to Clinical Trials in Alzheimer’s Disease (AD)(REACT-AD). 

The goal of the REACT-AD initiative is to use Ro’s telemedicine platform that serves a large and decentralized population to diversify the participants recruited for clinical trials. The hope is that telemedicine can facilitate this process by reducing some of the barriers that participants traditionally have faced, such as the need for transportation, time off work, or childcare for numerous trips to a trial facility, clinic, or lab for testing. The unique aspect of the study is that every step of recruitment, screening, and assessment can be completed in the comfort of patients’ homes and scheduled at their convenience.

Dr. Thambisetty will oversee the data analysis and publication of research findings emerging from REACT-AD. Ongoing research initiatives led by Dr. Thambisetty to identify effective Alzheimer’s and related dementias treatments include the Drug Repurposing for Effective Alzheimer’s Medicines (DREAM) initiative and the Preclinical Validation of Emerging and Novel Treatments for Alzheimer’s Disease (PREVENT-AD) study.

Ensuring equal access to clinical trials in Alzheimer’s disease for all individuals is not only a moral imperative but also sound scientific practice. We are excited to create a diverse and decentralized registry of trial-ready participants that will enable us to test the most promising AD treatments emerging from our ongoing research.

Madhav Thambisetty, MD, PhD, MBRF Trustee and Vice Chair

Learn More About the Project on ro.co

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